Your location targeting is defined here, at the ad group level.
Create an ad group for each market you want to target within your campaign.
Note that in this context, the Location does not necessarily refer to the location of the website visitor, but instead refers to the location of the housing market you want to advertise in. The location is primarily used to determine which search terms (keywords) will trigger your ads.
Edit a location (Ad Group) to add or remove keywords from your location, or to change its status (enabled vs paused).